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The story of the ladies on Wisteria Lane are moved ahead five years in time to when Susan flirts with her painter, Jackson Braddock, after Mike having been gone for so long, but not willing to commit to a relationship. Meanwhile, Bree denies all the help “her” company has received from her business partner Katherine, while Andrew feels like a doormat under Bree's influence. Lynette still has problems in getting Tom to see the light when it comes to their over exuberant trouble-making twins Porter and Preston. Also, Edie moves back to Wisteria Lane with a new husband: …
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Bree fails to notice the effect of her working long hours at cooking company is having on her home life as Orson, whom is revealed to have spent two years in prison after confessing to attempting to kill Mike, and whom begins to resent her. Meanwhile, Susan fails to notice that being friends isn't necessarily a bad thing when her ex-husband Mike, and her new painter boyfriend Jackson become friendly. Lynette fails to notice the impending doom regarding the new way she's bonded with one of her sons, Porter, after her loyal other son, Parker, gives her advice on how to …
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Danielle returns to Wisteria Lane with her son and new husband in tow, only to face psychological warfare from her mother, Bree, who naturally disapproves of how she is bringing up her son. Meanwhile, Susan tries to protect her son, MJ, from a bully, only to find out it's Gabrielle's daughter who is the bully, which puts a rift between the mothers. Gabrielle tries to deal with cutting costs when Carlos wants to sell their old car, and Gabby has too much pride to let it go. So, she turns to Andrew for help in borrowing his car to show off. Lynette continues to deal …
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Bree's new cookbook and entrepreneurial success has the women of Wisteria Lane feeling jealous, especially Lynette who's longing for a taste of her bread winning days as an ad executive leads her to lend an unsolicited hand to Bree's marketing plan. Meanwhile, M.J.'s drawing of a family portrait of him, Susan, and Jackson has left Mike feeling like he's not a presence in his son's life anymore. Gabrielle hatches a plan to have more sex with Carlos, but their daughter, Juanita, gets a first-hand view of it. Susan teaches a reluctant M.J. how to fall off his bicycle …
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Periodic flashbacks to the past five years explain some of the missing pieces that were left unanswered. Driven by his hidden and twisted agenda, Dave convinces Susan to throw Mrs. Karen McCluskey a surprise party for her 70th birthday. As everyone gets ready for the party, Jackson wants to take his relationship with Susan to the next level by moving in together. Susan flashes back to how she forced Mike to end their marriage, and how Jackson came into her life and who was turned on by her neurotic and unpredictable behavior. Gabrielle is concerned she might be …
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Gabrielle has a fit when one of Carlos's wealthy massage clients, Virginia Hildebrand, makes them an offer they can't refuse, but a startling discovery leaves Gabby second guessing. Meanwhile, Lynette grows suspicious that Tom is cheating on her with the sultry Anne Schilling, a promoter who wants to book Tom's new garage band for a show. One of the Scavo twins, Porter, gets grounded for getting into trouble with the law… again. Susan and Jackson break up when she wants to continue to keep their tryst casual, while he wants to move forward with their romance. Later,…
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Lynette and Tom uncover an unpleasant truth about Porter that he is romantically involved with the blond, femme fatal Anne Schilling. Meanwhile, Gabrielle suspects Carlos' best massage client, Virginia, has ulterior motives. Bree's moment of weakness with her cookbook could bring her great embarrassment and shame, while Katherine's not-so-little secret is unveiled. Susan learns of Jackson's true passion. Also, Mrs. McCluskey's sister, Roberta, unearths a disturbing fact about Dave when she discovers that he spent time in prison, and that he's connected to someone who …
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Susan's daughter, Julie, comes to visit with her surprising new boyfriend, an older man named Lloyd. Gabrielle uncovers the unsettling truth about Virgina Hildebrand's past and why she's obsessed with moving into the Solis' lives. Katherine has a confession to make to Susan that she is now involved with Mike. Meanwhile, Bree becomes more nervous when a reporter looks to expose her imperfections, since Bree's entire life is built around perfection. Lynette learns that Porter and his older love interest, Anne Schilling, plan to leave Fairview and run away. Lynette …
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In the aftermath of the devastating nightclub fire, Susan deals with the fact that the recovering Mike is now involved with Katherine. Meanwhile, Porter gets accused of setting the fire, and Lynette decides to protect him despite not believing his innocent claims that he did not start the fire. Lynette also confronts Annie in which she bribes her to leave town and never see Porter again. Bree deals with Orson's snoring habit resulting from his broken nose, and in trying to deal with her sleepless nights, has an unfortunate reaction to one too many sleeping pills to …
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As Carlos' sight begins to return, he begins to see what sacrifices Gabrielle made to keep her family intact, while Porter gets arrested after Dave tells the police he saw the boy coming out of the storeroom just before the fire. But when Porter tells Lynette and Tom about a separate crime that he committed by breaking into Edie's house to steal a gun to use against Annie's husband, Lynette takes great measures to try to sneak back in to Edie's house to return it unnoticed. Meanwhile, Bree deals with the revelation that Andrew'a latest beau is Orson's plastic surgeon,…
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Bree forces Andrew to bring Alex's common mother Melina to dinner, but the future in-laws instantly hate each-other, rivaling for their gay sons' presence at family holidays, and in whose town they'll live. Susan and Lee get so drunk they wake up in bed together. Bob discovers twins Porter and Preston switched places and refuses to risk disbarring for failing to report so by the next court date. So finds out the twins have phone contact and leans on Preston to help save bail, hence the business, by asking his brother back. Carlos intends to accept a feel good job in …
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Dave bunks in at Mike's after being thrown out by Edie, who ends up locked in a basement with Susan. Meanwhile, Katherine puts Mike on the hot seat by mentioning her offer to move away. Bree's future “son-in-law” Alex, defends Orson when she belittles his purchase savvy. Lynette finds out where her son, Porter, is hiding, which brings her face-to-face concerning the issues between her and her estranged mother Stella. Also, Gabrielle seeks to control her two unruly daughters when Carlos' new job keep him away long hours.
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Local handyman Eli Scruggs dies from a heart attack on his last day of work and the housewives remember moments when he affected their lives.
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Bree reaps the success of her new book by treating herself to a new car, which irks Lynette since she had to sell Tom's Mustang for some extra cash. Meanwhile, Susan is determined to send M.J. to the best school, even though she and Mike can't afford the high tuition. Gabrielle joins Edie's no nonsense boot camp to get herself back into shape. Also, Lee is conflicted over whether or not to tell Lynette and Tom some disturbing facts about Dave whom he begins to suspect of setting the nightclub fire and lying about Porter setting it.
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Susan starts her new job as a teacher's aide to MJ's school in order to give her son the best that she never had. But when Mike leaves their son in Katherine's care while he works, naturally in Susan's case, anger and jealousy pervade. Meanwhile, Lynette tells Tom that they may have to sell the Scavo's Pizzeria since business continues to go bad, but he stubbornly refuses to cave in. Carlos receives a generous bonus when Gabrielle discovers Carlos' boss' dirty little secret of him cheating on his wife. Also, Orson confronts Bree when he learns she's given Andrew a …
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In the aftermath of the Scavo Pizzara going under, Bree tells Lynette she'll help Tom secure a new job at her company. But even the best intentions will reach a tempestuous end when a dinner engagement set up results in both Lynette and Tom competing against each other for the job, and Bree discovers Orson's growing kleptomania habit. Meanwhile, Gabrielle finds herself in a precarious position when Carlos' adulterous boss, Brad, begins using Gaby to cover for himself as he continues to cheat on his wife. Susan becomes more unsettled after Katherine moves in with Mike …
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As Susan continues to work as a teachers' aide, she tries to stay on the reading teacher and her employer's, Jessie's, good side since she will be evaluating Susan's performance. But Jessie, who happens to be a closeted lesbian, mistakes Susan's stuttering and lame attempts to be friendly as come-ons. Meanwhile, Edie begins looking for more information at a local newspaper office on information on the people who died in Mike's car accident years earlier, and discovers the connection between the victims, and Dave, who continues to badger Mike into taking him and …
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Bree considers selling her cooking business to save her marriage to Orson, but soon goes back on her word when both of their egos get in the way. Meanwhile, Lynette is threatened by Lucy at her new office job, while Gabrielle and Carlos cross boundaries as Carlos has no time for her, and Lynette decides to play Lucy and Carlos against one another. Elsewhere, Katherine volunteers to accompany Mike and Dave on a camping trip while he plots to murder her with a gun he brings. Susan's ex-husband, Karl, returns and enrolls his troubled son, Evan, in her class where a …
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After Edie suddenly dies in a car accident, she narrates her story from beyond the grave when Susan, Bree, Gabrielle, Lynette, and Karen McCluskey travel out of town to visit Edie's estranged teenage son, Travers, at his boarding school to deliver her ashes to him. During the long car drive, each of the five women think back to their most significant time in Edie's life. Susan recalls how she first met the superficial and man-lusting Edie and how she taught the klutzy Susan how to deal with her place in the world. Lynette recalls how Edie took her to a rough biker bar…
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When Orson is admitted to the hospital after he attempts to rob an old woman whose house he breaks into, he's confident that nobody will believe her because of her senile personality. But later, Bree becomes suspicious of the truth, but keeps it to herself. Meanwhile, Tom and Gabrielle square-off against one another when Tom joins Gabrielle's new gardening club and she worries about a fellow member flirting with Tom, while Carlos saves Lynette after she falls and hits her head in the shower. Dave goes into a decline over Edie's death, and when Susan pays a visit to …
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Mike becomes more uncertain about his future with Katherine when M.J. asks if he is going to marry Katherine. Tom and Lynnette try out an experiment of having sex for 30 days straight to spruce up their troubled marriage. Bree asks Susan's ex-husband Karl, now a divorce lawyer, for representation for her divorce from Orson in order to deny him any percent of her catering business. Karl agrees to be Bree's lawyer, but only if she tries to get his trouble-making son, Evan, invited to M.J.'s sleepover. Elsewhere, Jackson suddenly returns in Susan life where he proposes …
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Susan and Jackson announce their engagement to everyone, which has Mike feeling uneasy about it and debates with himself a future with Katherine on proposing marriage as well. Dave becomes worried when he figures out that Jackson may have witnessed him setting the fire at the nightclub. He also gets worried when he accidentally overhears Susan confiding in Katherine that the upcoming marriage is fake in order to let Jackson stay in the country. Dave plots to remove Jackson with an anonymous phone call to the NRS authorities. Meanwhile, Karl persuades Bree to stage a …
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Gabrielle becomes upset when Carlos' family invites them over at his Aunt Connie's house where she asks them to look after Carlos' niece, Ana, for a while which the not-so-innocent youngster disrupts the Solises daily routine. Meanwhile, Lynette becomes angry at Tom when tells her that he wants to go back to college to seek more education for his job hunting when she thinks he desperately does not want to let go of his youth. The brutal battle of the sexes between Orson and Bree gets nasty when Orson discovers the storage locker, in Bree's name, with all of the stolen…
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Lynette accepts Tom's decision to go back to college. But when Lynette later finds out that she's pregnant with twins, they must decide what path their future will take. Meanwhile, Bree must decide how to finally rid herself of Orson and contend with the advances of Karl, her lawyer. Ana moves in with Gabrielle and Carlos over Gabby's objections that Ana is not who she claims to be when she begins throwing her weight around by slacking off and coercing the Scavo twins into doing her household chores. Also, Dave puts his final plan of revenge to kill M.J. in full force…